Cloderm Cream Not a Cookie-Cutter Topical Steroid

Cloderm® Cream for dry, cracked, and inflamed skin

Cloderm® Cream is an effective option for treating atopic dermatitis.

  • Provides Class IV efficacy with a good safety profile1-4
    • At day 14, significant efficacy was noted (71%) versus placebo (28%) P<0.001 (n=96)*
  • The pivalate group enhances lipid solubility1
  • Statistically significant (65%) improvement of symptoms at day 4 (versus placebo 31% P<0.001)4
  • Enhances epidermal barrier function5
  • Available in 45 g & 90 g tube and 75 g pump

*Objective criteria included decrease of erythema, edema, transudation and, if present, vesicles or bullae, papules, plaques, scaling, crusting, fissures, and lichenification.

Cloderm® Cream enhances epidermal barrier function5

Cloderm® Cream key ingredients:

1. White petrolatum
NO Lanolin
2. Mineral oil
NO Propylene glycol
3. Stearyl alcohol
NO Added fragrance

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Indication and Important Safety Information6

Cloderm® Cream is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses. The most common adverse events with Cloderm® Cream include burning, itching, irritation, dryness, and folliculitis. Cloderm® Cream is contraindicated in patients who are hypersensitive to any of the ingredients of this product. As with all topical corticosteroids, systemic absorption can produce reversible HPA-axis suppression.

See full Prescribing Information.

References: 1. Bikowski J, Pillai R, Shroot B. The position not the presence of the halogen in corticosteroids influences potency and side effects. J Drugs Dermatol. 2006;5(2):125-130. 2. Del Rosso J, Friedlander SF. Corticosteroids: options in the era of steroid-sparing therapy. J Am Acad Dermatol. 2005; 53(1 Suppl 1):s50-s58. 3. US Food and Drug Administration NDA 017765. Promius Pharma, LLC, Princeton, NJ: Aug 1977. 4. Rosenthal AL. Clocortolone pivalate: a paired comparison clinical trial of a new topical steroid in eczema/atopic dermatitis. Cutis. 1980;25(1):96-98. 5. Kircik LH. A study to assess the occlusivity and moisturization potential of three topical corticosteroid products using the skin trauma after razor shaving (STARS) bioassay. J Drugs Dermatol. 2014;13(5):582-585. 6. Cloderm [package insert]. Princeton, NJ: Promius Pharma, LLC; 2017.